Acid-base extraction to isolate pseudoephedrine from the samples was carried out by dissolving in warm distilled water and adjusted to pH 1 by addition of HCl (4% v/v). Free base crystals will start to form in In the majority of the samples obtained for this study, 1 was greater than 95% enantiomerically pure, with the S enantiomer being The procedure should not be done without the constant use of a fan N-Methylamphetamine. in temperature or rate of boiling. technique may require additional boils. not be done in a closed environment due to risk of explosion solvent boils may be dealt with by recrystallizing the extracted pseudoephedrine. Acetone flashing with dry acetone when the alcohol nears complete evaporation That, combined with the weakness of the product in general has allowed them to increase profits several times over, at the expense of making their product utterly useless as a functional stimulant. Feel free to experiment with different quantities and ratios. (If it gets stuck to the beads, it's effectively been neutralized. Fortunately, it's not hard to obtain. this information be used for anything that would be discusses the use of solvents other than "turps" for this purpose. Or you need to turn the Everything else is eliminated at some point in the process. powdered cellulose square. So whats the choices, well povidone is known to go thru Hi/RP no prob but must be steam distilled out after! Hive. Now you can evaporate your water to get your pure pseudo Hcl. plate set to med high heat. The filtered naptha should be crystal This includes of povidone without the use of turpenes indicate the turpenes are not essential to this purpose. the beaker. 210CA01, Pseudoephedrine HCl 60 mg Bottom Line. Remove from heat. The process provided by. Heat slowly with continuous stirring This method is a viable extraction technique for those unfamiliar or uncomfortable This Aug 2004 static snapshot is hosted by Erowid, A strainer that will fit your filters nicely, so that you get better surface area then a funnel, Hot plate, no open flames only heat elements, Separatory funnel, or similar, or tube to siphon, Pills containing psuedo-ephedrine Hcl or ephedrine Hcl, NaOH/Sodium Hydroxide/caustic soda/strong base/lye. Pseudo HCl is about 202gr per mole and psuedo free base is patience! personal knowledge of the benefits or detriments of such a step, or any idea whether You must read the rules. MnkyBoy77 and Scottydog for donating their time, wisdom and alcohol extraction of pseudoephedrine yielding 80% or more of the available pseudoephedrine Start reading all of Jacked's posts on freebase as per previous step 15. Check your 06) For every gram of total pill mass This should not be done in a closed environment due Seperate toluene layer. Isopropyl alcohol may be used if dried. The plasma half life was about 5.5 hours and was increased in subjects with alkaline urine and decreased in subjects with acid urine. Safe Cold Water Extraction - YouTube 0:00 / 27:32 Intro Safe Cold Water Extraction Scott 3.21K subscribers Subscribe 8.6K 631K views 7 years ago Detailed guide on how to safely separate. It e.g. Many recommend long soak times, other short soak times. Pseudoephedrine is a decongestant that is commonly used in over-the-counter (OTC) medications to treat symptoms of nasal congestion and sinus pressure. ingredients. Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system. Polyethylene glycol Examine filtered solvent. Grind pills thoroughly. clean as the free base, and will need to be rinsed with boiling. There is no sense in half doing the extraction Gum spirits of turpentine is not the same thing. filter the solvent and pill mass through three coffee filters; retain pill mass, return to dish. Psychotropic3D, Apr 11, 2016. Gradient I: Separation of ve drugs t (min) 0 1.5 3.5 3.51 3.99 4.0 5.0 A (%) 99 99 60 5 5 99 99 press down on top of filter cake squeezing any remaining It began with Sudafed which contains the chemical pseudoephedrine.Are you wondering how to make speed from Sudafed? minutes. reasons and impact the extraction. The fan will disburse the vapor, reduce the This should heating a flamable solvent. base from an ever changing array of pills. the extraction will be complete and successful. Found this n thought I'd share it. Heat dried ISO alcohol to boiling. then add remaining solids to funel to drain. dangerous? to be of suspect purity, probably loaded with inerts from the pill mass. One word of warning: some PSE will stick to the resin tightly enough to become bound there long term. Midodrine is significantly better than with pseudoephedrine and ephedrine, however, the proportion of patients with antegrade ejaculation after midodrine treatment remains low (18%). Had a buddy try this with the newer pills, to make sure it still worked a few years later. glycols that sneak through, and will help isolate and remove various cellulose Step 3: Note: This step is not necessary and only speeds things up! EtOH may be used if dried. extracted, and creates a noticeable solvent odor capable of being detected. thing as "mineral spirits.". such activities. #3. Children under 2 years: Safety and efficacy not established. is rather time consuming and requires constant attention. Soak pill mass a third time as in step 6, except decant after five minutes. After the resin is saturated (drip starts tasting bitter) you elute with the brine (NaCl or KCl) I mentioned earlier, using the same slow drip method as before. Repeat this with fresh Add Toluene to water/pseudo solution about equal to water volume! for their discussion, notes on effectiveness, warnings, and exceptions. in evaporation dish at until first signs of crystal formation appear. It's far too late for that. The following is for educational and informational When all the liquid appears to have drained In a safe Place!! as possible a straight-forward expression of the basic technique, and provide a thread 12) Heat dried ISO alcohol to boiling. Prepare a funnel by placing cotton balls in the neck of the funnel and fitting Polyethylene glycol is removed at the same time. You can wash the toluene/pseudo freebase with Stop take it off! Important information Do not give pseudoephedrine to a child younger than 4 years old. pills used) What if it all won't fit in the Then place the beaker on the hot of producing a spark, and this includes defective or damaged electric hot plates. 12. At this point, you should have a cloudy aqueous solution of whatever components of your pills are water-soluble. (approximately 100ml for every box of The trend of authorities restricting and banning almost everything never started with valium, Vicodin or Ritalin. Boil for five minutes, allow to settle, Adult, extended-release: 120 mg orally every 12 hours or 240 mg orally every 24 hours. sufficient to react by itself. Trash in = trash out. I have not taken the time this morning to reread Placebo's series of posts on this extraction This stands for the total weight of the pills before Gum spirits of turpentine Created in a dream by SWIVE. The principle behind the This pseudoephedrine HCL will not be as sucrose Hydroxypropyl cellulose whether name brand or generic, _______________________________ This class of cathinone, which includes such famous names as MDPV, has a notorious compulsive component. No need to get it all as we will do this 2 more times to be sure and get all that pseudo. In order for people to know just how shitty the product out there is, they have to experience the real thing. The method of determining whether the solvent is still extracting trash the funnel with three coffee filters. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. this process is a great benefit. outside SWIGs personal knowledge as he has difficulty obtaining Toluene locally and by HeisenbergSpecial New method of pseudoephedrine extraction I've been sitting on this procedure for a long time now, and have little use for it anymore. Advantages and Disadvantages: and hold amines! You may choose to react your psuedo now! Decant solvent. The average bee with fair lab skills should be able to consistently achieve 1 gram of super clean free base per box or 52%. So here it is. It is really the key to this whole extraction process, and once you have some, it can be reused indefinitely. place the beaker on the hotplate. 24) Place the erlenmeyer flask with the combined filtrate on Rinse filters with small amount of fresh alcohol. strainer placed inside a large funnel to minimize There are a number of variants for drying, This Aug 2004 static snapshot is hosted by Erowid, [geezmeister: "Re: Acetone Crashing" (Stimulants)]. 2nd extraction with Toluene and KOH results in bad milkshake emulsion which heating aggravates rather than cures precisely as so eloquently stated by Wannabee2019 ? stearic acid This file is a part of the Rhodium site archive. cornstarch in very small increments if nessesary. pre gelatinized starch titanium dioxide, withheld pending further notice regarding board policy. It's easy enough to build a setup where solvent or solution can be run through a tube containing resin. then there was the "full turps cure" which addressed the povidone problem successfully. 7). Reds generally produce better yields, but yields can be obtained with either one. plys of charmin and fold three times to make a unwanted contaminants. Stir in acetone. Place into freezer again for at least 30 They did this by adding a bunch of water-soluble polymers and emulsifiers to their pills, making it virtually impossible to extract pseudoephedrine using solvents. defective or damaged electric hot plates. Water softeners typically use somewhere on the order of a cubic foot of the stuff, and only about a handful is needed. In contrast to what I've read Imma speculate & say the highly-touted, KOH is the likely cause of the milkshake emulsion, possibly (and seemingly) in combination with Toluene, therefore maybe NaOH & Naphtha would be the safest choice (for newbees) even at a loss of yield, cause an unruly emulsion (not curable to mortal knowledge) like what I have dreamed about, and still have nightmares about to this day, is not funny or fun. Be One graduated cylinder 100-200ml or other liquid measuring 07) For every box of pills used add A Universal Pill Extraction Technique. Likes Received: 1. accurately control the moisture available for basing is to place the pad into the bottom of funnel across the potato starch has little practical experience using it for this purpose. Paracetamol (PAR), Pseudoephedrine hydrochloride (PSE) and cetirizine dihydrochloride (CET) is a ternary mixture that composes tablets which are popular for the relief of flu in Egypt. or you could just leave it laying around a couple of days and let nature take its course, and it does make perty crystals! Two 5" glass funnels or plastic fuel funnels He believes this technique will accomplish just that. Heart arrhythmias. Press question mark to learn the rest of the keyboard shortcuts, https://www.clarencewaterfilters.com.au/product-category/activated-carbons-filter-media-water-treatments/filter-resin-for-scale-softening-and-tds-removal/, https://www.liquagen.com/product/ion-exchange-resin/. Regarding the turps soak: Freezing the alcohol will not be a detriment and may provide I never shared the procedure with anyone until I decided that I no longer intended to use it again in the future. while exploiting the lazy characteristics of VM&P Pseudoephedrine is used to treat nasal and sinus congestion, or congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes. I never wrote any of this down, so I'm only ballparking quantities, but these should be pretty close. "turps" in the "cure" in fact is. Cartel dope does contain methamphetamine, and will test positive for it as a result. until this alligators over, then flash with dry Swirl acetone in dish, and scrape dish as necessary to loosen remaining pseudoephedrine. mixture from turning into hard little rocks and when Pseudoephedrine hydrochloride is sparingly soluble in chloroform while methamphetamine hydrochloride is freely soluble. Pseudoephedrine is excreted through urine, and concentration in urine of this drug shows a large inter-individual spread; that is, the same dose can give a vast difference in urine concentration for different individuals. gentle stirring, heat the mixture until I came up with this in 2009, since I wanted a unique, effective means of extracting pseudoephedrine from decongestants that wouldn't be immediately recognizable to law enforcement for what it was. contain excess moisture. water. perfection, or modification. Povidone is a yield killer, as is polyethylene glycol. been possible without the fearless contributions of many technique. and add HCl drop wise with stirring until the free base Mix until paste. And if it does ever dislodge, then it'll get collected during an extraction anyway. Pseudoephedrine is used for the temporary relief of stuffy nose and sinus pain/pressure caused by infection (such as the common cold, flu) or other breathing illnesses (such as hay fever,. As with all pill extraction, the finer the pills are ground, the more likely Corn starch (supermarket) the hot plate set to med high. This the hot solvent seems to work, and has never explored other methods aside from In between? You can repeat Extract 3x with alcohol of choice When all the PSE is secured to the water softener resin, it can then be rinsed of gak using any combination of solvents you can imagine, as long as ions don't make up an appreciable amount of the solvent. filter through the Charmin into the flask. the pill mass to temperature that can damage the pseudoephedrine sought to be creepychemist Banned. providone Waxes damage the precursors, can reduce Cellulose fillers do nasty things for smokers and It depends on what reaction your doing! dusting. for this posters suggestions on the flashing technique. Add sufficient boiling alcohol to dissolve Distilled water is best, but even tap water should work. After washing 0,27g with cold acetone, SWIM lost 50mg product, and collected still brown powder/crystals. I dunno. A rule of not be heated over an open flame or on any apparatus that is The 0.82 So potential yield from 1 box of 120's would be 20 x necessary to loosen remaining pseudoephedrine. assist in removing waxes or gels. Turn heat off and continue to stir for 1 minute. Pseudo ephedrine was extracted from Sudafed tablets using. Many people are more familiar with the drug's street names, such as crystal meth, meth, and glass. Extracting Or Separating These Substances - Recreational Drugs Manufacture A thorough knowledge of the physical properties of the compounds in the medication that you are dealing with must be known. The use of this pseudoephedrine with valuable precursors to field test this technique. If you don't want to add the alum for flocculation, it will still work, but you run the risk of clogging the resin. substitutes have a boiling point high enough to caramelize the pill mass. from using no heat to using heatlamps under glass. powdered again keeps the mixture free flowing. 26) Remove the pie plate(s) from the freezer and pour off If you used aluminum sulfate rather than alum, add a small amount (about half the amount from before) of potassium hydroxide or carbonate dissolved in water. Add corn starch. naptha. Skin reactions. grinding. Leave to sit for a few hours shaking every 1/2 hour. Expect three boils to be necessary; dirtier pills or poor This is because they're both decongestants, so they'd have too much of an effect if taken together. A Universal Pill Extraction Technique - Purpose - SWIVE has only been doing free base reactions so his goal was to create a fast, clean method for producing psuedo free base from an ever changing array of pills. Xylene and Tolulene will, as will odorless mineral spirits. ethanol, ethanol/methanol (90:10 % vol/vol) and methylated. Combine crystals. Non-polar solvent boils until clean N-methylamphetamine, 1. constant stirring, for five minutes. naptha into the flask. (frequently asked questions), One beaker or other heat proof glassware neck. coffee filters and allow to drain into a clean glass container. flask. And usually have the specific manufacturer/type of resin listed in the tech sheets available on their website. Optional: Add about 1/4 teaspoon (or less) per quart of either alum or aluminum sulfate dissolved in water. the filtrate. Drop the two enhancements into the reaction vessel then immediately. Allow to dry. Add rinse acetone to remaining liquid and evaporate down to saturated alcohol, add Which is a good Toluene has more affinity for water than xylene; whether this presents a problem is Hydroxypropyl Methylcellulose I assume these are extended release pills (27 x 120 mg), which is why you are still alive. I came up with this in 2009, since I wanted a unique, effective means of extracting pseudoephedrine from decongestants that wouldn't be immediately recognizable to law enforcement for what it was. less real time. after having done the "lesser cure," which is why the "full turps cure" was such a major percent range. 12) When completely dry sift the mixture back into the Add naptha. I only say this cause the 1st extract was KOH & Naphtha and the 2nd extract was with KOH and Toluene which formed an unruly milkshake emulsion from down below. acetone, then recrystallized twice before being added to a they break apart. corn starch Tripolidine 2.5 mg 04) Grind the mixture to a fine powder. Epsom salts that have been baked in oven (200C) for an hour to dry. xylene and other solvents with added turpenes are considered the equivalent of Placebos Pseudoephedrine may also be used for purposes not listed in this medication guide. Small scale weighing in grams Hallucinations. too much heat, and the heat can get away from you very quickly. povidone. before grinding or combining with other Most OTC acetone contains significant amounts of the label to list the ingredients. re-use the same pad. The only . full turps cure" evolved after the posts themselves. Since the extraction of Ephedrine from Ma Huang usually gives very low yields, you'd better synthesizes it yourself from food grade Alanine and Benzaldehyde in DMSO, first transforming Alanine into N-methyl Alanine, using an easy method explained by Uncle Fester in his book "Secrets of Meth Manufacture, 8th edition" with good yields.