But depending on the dosage your doctor prescribes for your condition, you may take as much as 20 mg per day. You may experience side effects during your treatment with Eliquis. These are considered drug-condition or drug-factor interactions. 4. Spinal procedures include lumbar punctures (spinal taps), spinal injections, and epidural injections. However, its always a good idea to talk with a doctor about any drug rashes as well as before you stop taking any particular medication. In clinical trials, some people taking Eliquis reported having blood in their urine, which could be a sign of bleeding in the kidneys. There are many possible triggers of these digestive problems. Warfarin is a blood thinner that can be more effective when restricting foods that are vitamin K-rich. As such, the most common side effects of Eliquis include: Bleeding Bruising more easily than normal Anemia Other common side effects of Eliquis may include: Allergic reaction (skin rash, itching, flushing) Fatigue Nausea Headaches Dizziness In studies, the majority of people taking Eliquis were ages 65 years and older. Message and data rates may apply. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually 81-162 milligrams a day), you should continue taking the aspirin unless your doctor instructs you otherwise. Before you start treatment with Eliquis, talk with your doctor about the possible side effects of this medication. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). Learn more. If you have minor bleeding that happens frequently or is bothersome, talk with your doctor. All decisions regarding patient care mustbe made with a healthcare provider, considering the unique characteristics of the patient. The conditions and factors to consider include: Allergic reaction. [For questions about the Program, call. Your doctor will tell you when you should stop taking ELIQUIS and when you may start taking it again. Talk to your pharmacist for more details. Additional symptoms are severe and can involve the internal organs, such as: Possible drugs that can cause DRESS include: DRESS is a very serious reaction that requires immediate medical attention. Talk to your healthcare team before any surgery, medical, or dental procedures. On one side of each tablet, there is a number indicating the dosage strength of the tablet (in milligrams). In the United States, apixaban is also approved to treat certain types of blood clots (deep vein thrombosis-DVT, pulmonary embolus-PE) and to prevent them from forming again. There arent any known interactions between Eliquis and alcohol. Do not run out of this medication. During pregnancy, this medication should be used only when clearly needed. They may recommend ways to ease your symptoms and determine whether you should keep taking Eliquis. Drug rashes, or drug eruptions, are reactions your skin may develop in response to certain drugs. Order your refills early to avoid running out of pills. In the early stages, DIC causes your blood to clot excessively. Note: Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. For example, if the rash is very itchy, an antihistamine or oral steroid can help manage the itching until the rash clears up. However, some of these rashes may be accompanied by itching or tenderness. Examples of commonly reported side effects of Eliquis. Do not stop taking it any earlier unless you have discussed it with your doctor first. Is my risk of side effects increased due to other medications that Im taking? These include severe urticaria, erythroderma, SJS/TEN, anticoagulant-induced skin necrosis, and DRESS. These include boxed warnings from the Food and Drug Administration (FDA). They can then use this information to adjust your treatment plan if needed. Eliquis hasnt been reported to cause other long-term side effects (side effects that last for a long time). Poison oak rash can produce a severe, painful rash. This fluid can be tested to help your doctor diagnose certain conditions. Warfarin is an anticoagulant medicine (blood thinner). At the hospital, you may be given intravenous steroids and hydration. Before taking Eliquis, there are certain precautions to consider. Talk to your healthcare team about the following: Tell your doctor if you are pregnant or breastfeeding, or planning to become pregnant or breastfeed. certain antibiotics, including tetracycline, SJS involves less than 10 percent of your body, a buildup of the drug that causes toxicity to the skin, a drug makes the skin more sensitive to sunlight, a viral infection and taking an antibiotic, a weakened immune system due to an underlying condition or other drug. You may have a higher risk of bleeding if you take ELIQUIS and take other medicines that increase your risk of bleeding, such as aspirin, nonsteroidal anti-inflammatory drugs (called NSAIDs), warfarin (COUMADIN), heparin, selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), and other medicines to help prevent or treat blood clots. A drug allergy is an allergic reaction to a medication. Like most drugs, Eliquis can cause an allergic reaction in some people. I was changed to Xarelto and the condition worsened and spread. If you stop taking Eliquis earlier than your doctor recommends, this increases your risk of developing blood clots. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, bleeding problems (such as bleeding of the stomach/intestines, bleeding in the brain), blood disorders (such as anemia, hemophilia, thrombocytopenia), recent major injury/surgery, stroke, a certain clotting disorder (antiphospholipid syndrome), frequent falls/injuries. Eliquis will likely make the bleeding worse. Most are minor and related to an increased risk of bleeding with this drug. Tell your doctor right away if you have tingling, numbness, or muscle weakness, especially in your legs and feet. People with triple-positive APS may have an increased risk of blood clots from Eliquis. What should I do if I become pregnant during Eliquis treatment? This rash may develop suddenly or within hours, but it can take up to several weeks in some cases. A fibrinogen activity test is used to determine the level of fibrinogen in your blood. Apixaban may increase the risk of bleeding in the pregnant woman, the unborn baby, and the newborn baby. What is ELIQUIS? However, if you have a spinal procedure such as a lumbar puncture (spinal tap) or epidural injection while taking Eliquis, it could cause a spinal or epidural hematoma (blood clot in your spine). This drug has two boxed warnings. Ask your doctor what other medications may be better options for you. Which one is right for you depends on a variety of different factors. * If you have a stroke after stopping Eliquis, this could lead to long-term problems. Use an electric razor when shaving and a soft toothbrush when brushing your teeth. Activation and first use of the Co-pay. Learn about common, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Keep your skin dry. More severe drug rashes, such as erythroderma, may cause permanent changes to skin pigmentation after treatment. Examples include: If your doctor confirms youve had a mild allergic reaction to Eliquis, theyll decide if you should continue using it. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). If youve had a heart valve replacement, your doctor will likely not prescribe Eliquis. ELIQUIS is a prescription medicine used to: Reduce the risk of stroke and blood clots in people who have atrial fibrillation (AFib), a type of irregular heartbeat, not caused by a heart valve problem. Bruising was a common side effect reported by people in studies of Eliquis. They may recommend scheduling your procedure when youll have the least amount of Eliquis in your body. It is unknown if this medication passes into breast milk. Your risk of developing a spinal or epidural blood clot is higher if: If you take ELIQUIS and receive spinal anesthesia or have a spinal puncture, your doctor should watch you closely for symptoms of spinal or epidural blood clots or bleeding. If you have constipation or diarrhea with Eliquis, talk with your doctor. Eliquis hasnt been reported to cause kidney-related side effects, such as kidney damage or reduced kidney function. Do not stop taking this medication without consulting your doctor. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Side effects of 2.5-mg vs. 5-mg strengths, nonsteroidal anti-inflammatory drugs (NSAIDs), selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/202155s034lbl.pdf, Cardiovascular health: Insomnia linked to greater risk of heart attack. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. Eliquis has a boxed warning for the risk of spinal blood clots with spinal procedures. If you have kidney problems, your doctor may recommend a lower dose of Eliquis for you. For People at Risk of Stroke due to AFib Not Caused by a Heart Valve Problem. Do not change your dose or stop taking ELIQUIS unless your doctor tells you to. ELIQUIS (apixaban) is not for patients with artificial heart valves. To help you remember, take it at the same times each day. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. My doctor prescribed ELIQUIS (apixaban) for: To Reduce Stroke Risk Due to AFib Not Caused by a Heart Valve Problem. Physical examination revealed diffuse palpable tender non-blanching violaceous coalescent macules and patches on both thighs and calves ( figure 1) with purple bullae overlying a patch on the left dorsal fifth toe and the right medial calf. You can learn more about how we ensure our content is accurate and current by reading our. Artificial heart valve. This medication is a blood thinner and increases your risk of bleeding. Find out how to know if you have one and what to do about it. We avoid using tertiary references. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS. If you have concerns about risk of spinal blood clots during Eliquis treatment, talk with your doctor or pharmacist. As with other drugs, Eliquis can cause side effects (also known as adverse effects). This could raise your risk of side effects. Can diet help improve depression symptoms? This clot may press on your spinal cord, which could cause long lasting or even permanent paralysis. Eliquis may not be right for you if you have certain medical conditions. Active bleeding. Is the ketogenic diet right for autoimmune conditions? Bruises develop when capillaries burst after an impact, while blood clots occur when an injury damages blood vessels. Your doctor can recommend how long youll need to take the drug. Other drugs that have the same active ingredients (e.g. Seek immediate medical attention if you think this is the type of rash you have. If you notice other effects not listed above, contact your doctor or pharmacist. Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA). I've been on Apixaban for a 2 or 3 of years and over the last year I've started to have skin problems. You are about to leave the Bristol Myers Squibb and Pfizer ELIQUIS.com site. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS. If you have liver problems, Eliquis may build up in your body. There are many things people can eat and drink that may help keep the blood thin and reduce the chances of developing dangerous clots. For people taking ELIQUIS (apixaban) for atrial fibrillation: Do not stop taking ELIQUIS without talking to the doctor who prescribed it for you.