I will note that it is truly astounding how many statements that a supposed expert in immunology and vaccines can make that are just plain out-and-out wrong. The ongoing phase 3 trial of an adenovirus-vectored spike-based vaccine (Johnson & Johnson, NCT04505722) in South Africa, where the 501Y.V2 (B.1.351) strain with the Glu484Lys substitution is rapidly replacing pre-existing variants,11 might provide an opportunity to examine this question. Basically, its a race against evolution to get as many people as possible vaccinated before the virus can evolve resistance to the vaccine, and were fortunate that, contrary to Bossches claim, SARs-CoV-2 does not mutate very fast for an RNA virus. However, Dr. Vanden Bossches claims to have worked with the Gates Foundation, GAVI, and other vaccine-related enterprises does seem to be legitimate, which makes me wonder: Has he gone crank or is he a grifter? He also states that hes worked with GAVI: The Vaccine Alliance and the Bill and Melinda Gates Foundation, although searching the websites, I could find no reference to him other than a report written by him and others to GAVI about progress on an Ebola vaccine. Lets compare Dr. Vanden Bossches letter to what Wakefield wrote back in 2019. De serie is bedacht en geproduceerd door Thomas Van Goethem en is een coproductie tussen Fabric Magic en Ketnet, die de serie ook uitzendt.Elke aflevering bevat twee musicalnummers, telkens . Exploring issues and controversies in the relationship between science and medicine. Integendeel, zegt vaccinoloog Corinne Vandermeulen (KU Leuven), en ze somt de epidemien op die in het verleden net onder controle gebracht zijn door te vaccineren: Cholera, ebola, polio. 1. This inevitably leads to enhanced natural selection and adaptation of more invasive immune escape variants, 2/4 6 37 Honderdduizenden mensen zagen zijn boodschap intussen. Dit standpunt is niet onomstreden. My statements are based on nothing else but science. The current monkeypox outbreak is a result of the Covid vaccinations that are connected to Covid reinfections and the related reactivation of cytotoxic t-cells, claims Dr. Vanden Bossche. A recent review article suggests that immune escape by variants of SARS-CoV-2 is a possibility, but one that hasnt been definitively observed or demonstrated yet: So is there cause for concern? Sounds familiar: suboptimal immune pressure + viral variant! They do not. Seriously, as a vaccine expert, how is it that Dr. Vanden Bossche does not know this? "Hoe zou dat ook moeten werken? At this point, I will also mention that, because Ed Nirenberg produced an excellent rebuttal of Dr. Vanden Bossches mangling of immunology in his letter, Ill stick more to my lane (mostly, anyway), although there will be some overlap. By Geert Van den Bossche Nov 6, 2018 Activity Leefbaarheid en mobiliteit zijn belangrijke uitdagingen binnen de Deltaregio. De Belgische wetenschapper Geert Vanden Bossche heeft het internet veroverd met zijn waarschuwing voor een wereldwijde ramp: de massale coronavaccinaties zouden een virusvariant kunnen creren die tegen de vaccins bestand is waardoor veel doden zouden vallen. Follow More from Medium Mehek Kapoor in. The resulting type of immune response is unprecedented and licenses the host immune system to readily eliminate infection or to cure disease across a broad range of unrelated pathogens and/ or mammalian species. These assumptions come without scientific studies or data to support them and indeed are not always reasonable. Zie het als een kopieermachine, legt immunoloog Hans-Willem Snoeck (Columbia University, New York)op zijn beurt uit. Vanden Bossche vraagt zich af of de reacties via VRTNWS en Knack berusten op onwetendheid dan wel op het moedwillig verdraaien van de feiten en roept de ons aller gekende experten op het wetenschappelijk debat aan te gaan. Heres the crux of his concern, in which he likens escape from vaccine immunity to antibiotic resistance: THE key question is: why does nobody seem to bother about viral immune escape? The molecular weight cut-off of microcapsules is determined by the reaction between alginate and polylysine. More recently, he set up his own website to publicize his letter: We've put together a website to gather all information, scientific documents and interviews I've posted on this public health emergency. Je krijgt daardoor minder besmettingen en daardoor ook minder mutaties. Bij sommige besmettingen kunnen NK-cellen wl specifieker te werk gaan, stipt immunoloog Herman Favoreel (Universiteit Gent) aan. Zijn pleidooi werd vooral opgevangen en verspreid in de vaccin-kritische beweging. This problem will be exacerbated, he claims, because people who have been vaccinated (and/or social distancing and staying inside during the pandemic) will be less capable of fighting off those strains than someone who has not been vaccinated. Failure to comply with these requirements is at risk of granting microbes a chance to survive and hence, may cause the disease to fare [sic] up. Mass vaccination programs, he claims, are "turning vaccinees into asymptomatic carriers" who can unknowingly spread these more dangerous strains by "shedding infectious variants." [3] [4] Het probleem is volgens Vanden Bossche dat de specifieke antistoffen van het vaccin (dat gebaseerd is op de oorspronkelijke Wuhan-variant) steeds minder werkzaam zullen zijn. The role of spike protein variability inT cell immunity is likely to be elucidated in experimental studies in the next few months; a priori, the enhanced repertoire of T cell epitopes makes the loss of cytotoxic activity or recognition improbable. This sharply contrasts with conventional targeting of natural immune responses as induced by conventional vaccines. De nieuwsombudsman van VRT NWS ontving veel vragen over Vanden Bossche en ook de meeste berichten die we kregen via check@vrtnws.be gingen de voorbije weken over Vanden Bossche. After all, if a human vaccine lets deadlier versions of a disease flourish, that is all the more reason to be protected from those deadly strains. View geert vanden bossche's profile on LinkedIn, the world's largest professional community. He claims that its because theres so much coronavirus circulating and so many people might produce suboptimal levels of antibody to the virus that, as is the case when antibiotics are used at levels too low to eliminate bacteria and thereby result in strong evolutionary selection for resistant strains of bacteria, a mass vaccination program is doomed to result in resistant variants of coronavirus, particularly when the vaccination program has started out targeted: As if this was not already heavily compromising innate immune defense in this population segment, there comes yet another force into play that will dramatically enhance morbidity and mortality rates in the younger age groups: MASS VACCINATION of the ELDERLY. Je kan gerust zon idee als het NK-vaccin voorstellen, vindt Leroux-Roels, Maar het lijkt me beter om in een epidemie te werken met een benadering waarvan we weten dat ze veilig is en op korte termijn werkt. See the complete profile on LinkedIn and discover geert . 42(3) . Vanden Bossche has created a scientific-sounding argument that vaccination will encourage the production of COVID-19 variants that our immune systems will be unprepared to fight. As a dedicated virologist and vaccine expert I only make an exception when health authorities allow vaccines to be administered in ways that threaten public health, most certainly when scientific evidence is being ignored. ), vertelde Vanden Bossche tijdens een congres in Ohio begin deze maand. Wij staken ons licht op bij verschillende vakgenoten en hun oordeel over zijn stelling is eensluidend: Technische nonsens. Ik ben onafhankelijk en neutraal, heb geen aandelen bij vaccin fabrikanten en ben niet gebonden aan contracten die bepalen wat ik al dan niet mag zeggen. By educating these cells in ways that enable them to durably recognize and target Coronavirus-infected cells, our immune system could be perfectly armed for a targeted atack to the universe of Coronaviruses prior to exposure. and to induce herd immunity (which is exactly the opposite of what current Covid-19 vaccines do as those increasingly turn vaccine recipients into asymptomatic carriers who are shedding virus). Amusingly, as I was looking this post over earlier this morning for a final edit, I saw that no less a grifter than RFK Jr. himself had published a rebuttal to Dr. Vanden Bossches open letter by someone named Rosemary Frei, The Not-So-Hidden Agenda Behind Bossches Concern Over COVID Mass Vaccination. If you claim to be not antivaccine but your message is so attractive to a rabid antivaxxer and leader of the antivaccine movement like Del Bigtree that he spends an hour promoting it, you are either deluding yourself about being not antivaccine, or youre a useful idiot for the antivaccine movement, possibly both. In verschillende video's op YouTube waarschuwt de Belgische wetenschapper Geert Vanden Bossche voor een ramp nog groter dan de coronacrisis zelf. Sure, we dont yet have a firm grasp of how much the vaccine decreases transmission, but there is good emerging evidence that it does significantly decrease transmission. [2], Na een carrire in de academische wereld in Belgi en Duitsland werkte Vanden Bossche bij verscheidene bedrijven aan de ontwikkeling van vaccins (GSK Biologicals, Novartis Vaccines, Solvay Biologicals). Geert Vanden Bossche is a scientist who published an open letter warning of global catastrophe due to deadly variants of COVID-19 selected for by mass vaccination. Hij waarschuwt met name voor de risico's van het vaccineren van kinderen met mRNA-vaccins. The more extensively the later age group will be vaccinated and hence, protected, the more the virus is forced to continue causing disease in younger age groups. Archeologen tonen verborgen gang die ze ontdekten in 4.500 jaar oude piramide van Cheops in Egypte, Het kraakpaleis werd ontruimd, terwijl het een mogelijk alternatief biedt, Open brief: Boos op onze politieke leiders. 70 ID:bdLlFOqq0 >>1 3 . Samen zetten zij zich evenwel af tegen het beleid van keizer Jozef II en streefden zij naar de onafhankelijkheid van de Zuidelijke Nederlanden, hetgeen leidde tot de Brabantse Omwenteling (1789 - 1790). EnVanden Bossches alternatieve NK-vaccin bestaat nog niet. Feb 18 Replying to @RespectingFA My intention was to write a scientific work to provide my fellow scientists with the indispensable insight that they now so often lack. VRT en Knack, kijk eens in de spiegel en laat ons toe de interviews die ik met jullie had publiek te maken. Waiting for Vanden Bossche's "universal vaccine" is no way to win such a race. Hij was daarbij kritisch over de veiligheid van een ebolavaccin. He held adjunct faculty appointments at universities in Belgium and Germany. Hij wijst erop dat hij geen soort van hobby viroloog is zoals hij wordt weggezet in de media en benoemt zijn ervaringen en diplomas waaronder bepaalde zaken die niet veel Vlamingen hem hebben voorgedaan. Skip to main content Geert Van Den Bossche En dan moet je weten dat het coronavirus eigenlijk niet zo heel veel muteert in vergelijking met bijvoorbeeld de griep. Hoe minder je kopieert, hoe kleiner de kans dat er een kopieerfout gebeurt.. "In de wetenschap weten we nog lang niet alles, dat klopt, maar als iemand een nieuwe claim maakt moet hij wel uitleggen hoe hij dat onderzocht heeft, wie de controlegroep was, enzoverder. Quote Tweets. Its another step in the decades-long erasure of the fact that our sophisticated and highly effective immune systems work well and dont need any assistance from the biomedical/pharmaceutical industry. It is, as McGill's Jonathan Jarry wrote and as Yale's Omer told us, a classic example of the appeal-to-nature fallacy that invokes the primacy of natural solutions, mechanisms, or substances over those deemed unnatural and human created. Because his proposed solution appears to be a fantasy, its effect would be to stop vaccinations completely and replace them with nothing. NK cells are pathogen destroying cells that are part of the innate immune system. 39. It is precisely this type of highly specific, high affinity Abs that current Covid-19 vaccines are inducing. Noam Chomsky: De hele wereld wil een onderhandeld einde aan deze oorlog, alleen het Westen niet, Noam Chomsky: Wat Belgi deed in 1960 in Congo is een van de ergste misdaden van de 20ste eeuw, creative commons Snopes and the Snopes.com logo are registered service marks of Snopes.com, Image Via Screencapture / geertvandenbossche.org. One such claim that I hadnt yet seen is another favorite antivax claim, although admittedly its a rather niche claim in that you dont hear it too often. Geert Vanden Bossche is een Belgische dierenarts, viroloog, zelfverklaard mRNA-vaccinatie specialist en onafhankelijk onderzoeker en adviseur op het gebied van vaccins. #LikeMe is een Belgische muzikale jeugdserie die wordt uitgezonden sinds 2019. This is an absurdly counterproductive solution if Vanden Bossche were truly concerned about variants. Deze sfeer is mee geschept door de experten en de media. Laat ons een sereen, publiek debat voeren over de vragen die van belang zijn in plaats van te twitteren. Fact-checkers noemt Vanden Bossche marionetten van een georkestreerde smaadcampagne die zich als leek willen mengen in zulk complex gegeven als virologie. Geert Vandenbossche, Patric Van Oostveldt (UGent) , Jo Demeester (UGent) and Jean Paul Remon (UGent) ( 1993 ) BIOTECHNOLOGY AND BIOENGINEERING. His argument sounds a lot like an argument Andrew Wakefield once made for MMR. Het publiekelijk schofferen van wetenshappers of mensen die hun job kwijt raken of beledigd worden omdat ze zich kritisch uitspreken, zulke zaken passen niet in onze cultuur van vrije meningsuiting en open debat. As I go through Dr. Vanden Bossches open letter, Ill point out the similarities, while also noting differences when they occur. In verschillende video's op YouTube waarschuwt de Belgische wetenschapper Geert Vanden Bossche voor een ramp nog groter dan de coronacrisis zelf. Hij beweert dat je door veel te vaccineren tijdens een pandemie een nieuwe en veel dodelijkere vorm van het virus kan creren. A company claiming to develop such a product is currently registered to an address identified on Yelp as his veterinary practice. One benefit of several current COVID-19 vaccines, most notably the mRNA vaccines, is that they can be easily modified to induce the development of antibodies programmed specifically to deal with whatever new variants crop up. Such claims are generally an offshoot of another favorite antivaccine claim, namely that the diseases being vaccinated against are so innocuous that vaccinating against them is overkill and allowing infection and natural herd immunity to occur is better, a trope that has also been resurrected about COVID-19, a disease thats killed well north of 500K people in just the US in a little over a year. Volg VRT NWS op uw smartphone of tablet via de VRT NWS-app. The mechanism he invokes is that vaccine-produced antibodies will "outcompete" the more general defenses of the innate immune system. Experts and politicians have remained silent while obviously still eager to talk about relaxing infection prevention rules and springtime freedom. It has been observed that over time Mareks disease virus has become more virulent, and this has been attributed classically to a leaky vaccine effect. As a scientist I do not usually appeal to any platform of this kind to make a stand on vaccine-related topics. Dont you see? De experten zitten op twitter fact-checkers te liken en roepen mij op aan de juiste kant te staan. ], Ive frequently discussed how in the age of the pandemic, at least in terms of antivaccine misinformation and pseudoscience, everything old is new again. Transformation is rapidly becoming the key to survive as an organsisation. David H. Gorski, MD, PhD, FACS is a surgical oncologist at the Barbara Ann Karmanos Cancer Institute specializing in breast cancer surgery, where he also serves as the American College of Surgeons Committee on Cancer Liaison Physician as well as an Associate Professor of Surgery and member of the faculty of the Graduate Program in Cancer Biology at Wayne State University. Claims that Belgium has the best fries in the world! He reminds me of another doctor who spread misinformation about COVID-19 vaccination based on an unbending principle of immunology to justify his concerns, without any clinical or epidemiological evidence to support it. [1] Zijn proefschrift gaat over veranderingen in oppervlakte-eigenschappen van virale deeltjes en hun infectieus gedrag. However, as we age, we will increasingly face situations where our innate immunity (often called the first line of immune defense) is not strong enough to halt the pathogen at the portal of entry (mostly mucosal barriers like respiratory or intestinal epithelia). And so am I. I searched PubMed for what I expected to be an extensive publication record on vaccines and foundeight publications, the most recent of which was from 1994 and none of which have anything to do with vaccines. Unfortunately, Dr. Vanden Bossches open letter has gone viral and is being spread on antivaccine social media everywhere as slam dunk evidence that COVID-19 vaccines will cause a global catastrophe by selecting for the evolution of highly transmissible and deadly variants of COVID-19 that will escape immunity due to vaccines. Dr. Vanden Bossche has also taken to social media to air his concerns, and his message has been enthusiastically embraced by antivaxxers: Lets just say this. Well, similar to the rules applying to classical antimicrobial antibiotics, it is paramount that our self-made antiviral antbiotcs [sic] are made available in sufficient concentration and are tailored at the specific features of our enemy. Ill refer you to Nirenbergs demolition of Dr. Vanden Bossches nonsense about innate immunity, as he explains why its nonsense better than I can. Again, this is an argument antivaxxers have made dating back at least to the pertussis vaccine. So, as we grow up, we increasingly mount pathogen-specific immunity, including highly specific Abs. Reality aside, invoking the innate immune system provides two rhetorical benefits. This new type of vaccines harnesses the power of the immune system by unlocking the untapped potential of self-centered Natural Killer (NK) cells capable of recognising these unconventional antigens. The solution to that risk is to vaccinate as many people as quickly as possible, thereby reducing both transmission of the virus and the number of environments in which mutations could occur. So its not surprising that Dr. Vanden Bossches letter reminds me of Andrew Wakefields warning about the MMR vaccine. Dat geeft de hoogst mogelijke bescherming en zal de verspreiding van het virus dus nog verder naar omlaag duwen. Aert van den Bossche or the Master of the Crispinus and Crispinianus-Legend (also known as Aert Panhedel, Aert van Panhedel, Arnoul de Panhedel, Arnoul Vanden Bossche and Harnoult van den Boske) was an Early Netherlandish painter of altarpieces, active in Brussels and Bruges in the late 15th century. Dr. Geert Vanden Bossche is a veterinary doctor who also has a Ph.D. in virology. Dat komt doordat ons immuunsysteem voor een virus heel moeilijk te omzeilen is. 1995 - 2023 by Snopes Media Group Inc.